Contact Admin. Type 1 diabetes can be diagnosed at an early presymptomatic stage by the detection of islet autoantibodies. The Fr1da study aims to assess whether early staging of type 1 diabetes 1 is feasible at a population-based level, 2 prevents severe metabolic decompensation observed at the clinical manifestation of type 1 diabetes and 3 reduces psychological distress through preventive teaching and care.
A venous blood sample is also obtained to confirm the autoantibody status of children with at least two autoantibodies. Children with confirmed multiple islet autoantibodies are diagnosed with pre-type 1 diabetes. These children and their parents are invited to participate in an education and counselling programme at a local diabetes centre.
Depression and anxiety, and burden of early diagnosis are also assessed. Of the Bavarian paediatricians, Capillary blood collection was sufficient in volume for islet autoantibody detection in Staging for early type 1 diabetes within a public health setting appears to be feasible.
The study may set new standards for the early diagnosis of type 1 diabetes and education. The study uses a novel approach of early diagnosis of type 1 diabetes to prevent diabetic ketoacidosis and improve care.
The study is performed in children at an age that maximises the likelihood of achieving early diagnosis of childhood diabetes. Measurement of psychological impact of early diagnosis will allow impact on family well-being to be evaluated.
